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. 2019 Dec 26;19:522. doi: 10.1186/s12884-019-2641-8

Table 1.

Pregnancy complications in normal controls and women with Wilson disease

Group (n) Age at pregnancy (y), mean ± SD Gravida Pregnancy outcomes, n (%) Complications, n (%) Pregnancy complications (%)
Success Failure Extremity edema Jaundice Ascites Hyper-tension Hyper-glycemia Hepatic injury Premature rupture of membranes Hydramnios Oligohydramnios
WD group (75) 27.72 ± 2.79 117 108 (92.3) 9 (7.7) 105 (78.4) 3 (2.2) 3 (2.2) 3 (2.2) 2 (1.5) 18 (13.4) 5 (50.0) 2 (20.0) 3 (30.0)
Control group (22) 27.41 ± 3.85 31 30 (96.8) 1 (3.2) 30 (81.1) 0 (0) 0 (0) 0 (0) 5 (13.5) 2 (5.4) 2 (66.7) 1 (33.3) 0 (0)
t/χ2 0.352a 0.229b 10.482c 1.229c
P 0.728 0.632 0.036 1.000

a t-value

b Continuously corrected chi-square value

c Chi-square value of Fisher’s exact test; mean ± SD