. 2019 Dec 26;11:109. doi: 10.1186/s13195-019-0565-1

Table 2.

Means and standard deviations by symptomatic diagnostic group (subjective cognitive decline or mild cognitive impairment), sex, and Aβ/P-tau status for demographics; memory and global cognitive scores, hippocampal and total intracranial volumes; and number of APOE ε4 carriers

	Subjective cognitive decline (SCD)				Mild cognitive impairment (MCI)
	Men		Women		Men		Women
	Aβ/P-tau+	Aβ/P-tau−	Aβ/P-tau+	Aβ/P-tau−	Aβ/P-tau+	Aβ/P-tau−	Aβ/P-tau+	Aβ/P-tau−
	(N = 34)	(N = 51)	(N = 25)	(N = 76)	(N = 74)	(N = 75)	(N = 63)	(N = 34)
Age	72.59 (5.37) ^a,b	70.22 (5.46) ^a,b	70.63 (4.84) ^a,b	69.78 (5.69) ^a,b	72.35 (5.13) ^a	69.59 (5.74) ^a	71.37 (4.88) ^a	69.76 (5.52) ^a
Education	11.71 (3.84) ^a	13.00 (3.59) ^a	11.60 (3.33) ^a	11.97 (3.30) ^a	11.62 (3.49) ^a	10.71 (3.48) ^a	11.44 (3.07) ^a	10.47 (3.13) ^a
ADAS Delayed Word Recall Omissions (/10)	4.12 (1.89)	3.38 (1.89)	5.06 (3.02)	4.73 (2.80)	6.91 (2.06) ^a	5.92 (2.10) ^a	7.43 (1.81) ^a	5.24 (2.69) ^a
MMSE total score	28.35 (1.54)	28.92 (1.29)	27.88 (1.88)	27.74 (1.73)	26.65 (1.67)	27.56 (1.85)	26.84 (1.79)	27.62 (1.88)
Total intracranial volume	1.7 × 10⁶ (1.1 × 10⁵)	1.7 × 10⁶ (1.3 × 10⁵)	1.5 × 10⁶ (1.1 × 10⁵)	1.5 × 10⁶ (1.2 × 10⁵)	1.7 × 10⁶ (1.3 × 10⁵)	1.7 × 10⁶ (1.4 × 10⁵)	1.5 × 10⁶ (1.2 × 10⁵)	1.5 × 10⁶ (1.2 × 10⁵)
Total hippocampal volume	7.2 × 10³ (1.1 × 10³)	7.7 × 10³ (1.3 × 10³)	6.8 × 10³ (1.3 × 10³)	6.7 × 10³ (1.1 × 10³)	6.7 × 10³ (1.1 × 10³)	7.2 × 10³ (1.3 × 10³)	6.1 × 10³ (1.0 × 10³)	6.6 × 10³ (1.2 × 10³)
APOE ε4 carriers	21 ^a	14 ^a	17 ^a	21 ^a	55 ^a	20 ^a	46 ^a	6 ^a

Abbreviations: Aβ/P-tau+ amyloid beta/P-tau positive, ADAS Alzheimer’s Disease Assessment Scale, APOE apolipoprotein E, MMSE Mini-Mental State Examination

^aDiffers by Aβ/P-tau+ within diagnostic group, p < 0.05

^bDiffers by sex within diagnostic group, p < 0.05

Significant differences in these variables by Aβ/P-tau status and sex within each diagnostic group are indicated by superscript