Table 1.

The module-inferred functional binding target gene sets have equal or better biological significance than pure knockout-inferred direct regulatory targets

Biological Aspects		Results
Ontology	Biological	128 (70.3%) TFs showed equal or better log enrichment scores
Enrichment	Process	in module-inferred functional binding target genes while only
		54 (29.7%) TFs showed higher log enrichment scores in the
		direct regulatory data.
	Molecular	109 (59.9%) TFs showed equal or better log enrichment scores
	Function	in module-inferred functional binding target genes while only
		73 (40.1%) TFs showed higher log enrichment scores in the
		direct regulatory data.
	Cellular	150 (82.4%) TFs showed equal or better log enrichment scores
	Component	in module-inferred functional binding target genes while only
		34 (18.7%) TFs showed higher log enrichment scores in the
		direct regulatory data.
Protein Interaction		68 (37.4%) of the module-inferred functional binding gene
Prevalence		sets reveled prevalence of protein interaction while only
		13 (7.1%) direct regulatory gene sets did.
Expression		Module-inferred functional binding genes had higher
Coherence		expression coherence in 32 different conditions while in no
		condition the direct regulatory data got higher expression
		coherence.