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. 2019 Dec 26;24:72. doi: 10.1186/s11658-019-0198-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Circ-CAMK2A is significantly up-regulated in LUAD. a Heat map of the differentially expressed genes in 5 LUAD and matched non-cancerous tissues (GSE101586). b Schematic representation of circ-CAMK2A derived from the back splicing of CAMK2A exons 16 and 17. c qRT-PCR analysis for circ-CAMK2A expression in 58 pairs of LUAD and adjacent non-cancerous tissues. d qRT-PCR analysis for circ-CAMK2A expression in LUAD cell lines. e Overall survival curve of LUAD patients with low or high circ-CAMK2A expression (based on median circ-CAMK2A value)