Fig. 2.

Circ-CAMK2A promotes LUAD cell migration and invasion both in vitro and in vivo. a qRT-PCR analysis for circ-CAMK2A overexpression and knockout efficiency in A549 and HCC827 cells, respectively. b CCK-8 assay in circ-CAMK2A-overexpressing A549 and circ-CAMK2A-silencing HCC827 cells at 0 h, 24 h, 48 h, and 72 h. c-d Wound healing assay in circ-CAMK2A-overexpressing A549 (c) and circ-CAMK2A-silencing HCC827 (d) cells at 0 h, 48 h. e Transwell invasion assay in circ-CAMK2A-overexpressing A549 and circ-CAMK2A-silencing HCC827 cells. f, g H&E staining of lung tissues in nude mice after injection with transfected A549 or HCC827 cells (n = 6 for each group). **p < 0.01