Table 2.

Numbers, amyloid PET positive percentage, and plasma biomarkers in APOE ε4 carriers and non-carriers

APOE genotype	ε4 carriers	ε4 non-carriers
	ε4 carriers (ε2ε4, ε3ε4, ε4ε4)	All ε4 non-carriers (ε2ε2, ε2ε3, ε3ε3)	ε4 carriers (ε2ε2, ε2ε3)
Amyloid PET+%	85.7%	26.3%	0
Plasma Aβ1–40 (pg/ml)	47.1 ± 7.2	50.9 ± 7.4	50.0 ± 8.5
Plasma Aβ1–42 (pg/ml)	17.9 ± 2.9	16.7 ± 2.9	16.5 ± 2.7
Plasma tau (pg/ml)	24.7 ± 9.9	19.3 ± 9.5*	18.8 ± 8.2
Plasma Aβ1–42/Aβ1–40	0.396 ± 0.117	0.343 ± 0.111	0.349 ± 0.126
Plasma Aβ1–42xtau (pg2/ml2)	468.2 ± 262.2	348.6 ± 242.1	331.0 ± 208.6

Abbreviations: Aβ Amyloid β, PET positron emission tomography

*P value < 0.05: ε4 carriers vs ε4 non-carriers