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. 2019 Nov 29;29(1):52–65. doi: 10.1002/pro.3730

Table 3.

Ligand‐gated ion channels in the PDB archive

Alla Cyclic nucleotide‐gated ion channel activity Extracellular ligand‐gated ion channel activity Intracellular ligand‐gated ion channel activity Ligand‐gated anion channel activity Ligand‐gated cation channel activity Ligand‐gated ion channel activity involved in regulation of presynaptic membrane potential
Structures 968 38 647 241 88 865 159

MX

(resolution)

685

(1.15–7.4 Å)

26

(1.65–3.28 Å)

506

(1.15–4.79 Å)

122

(1.21–7.4 Å)

59

(1.55–3.8 Å)

612

(1.15–7.4 Å)

115

(1.24–3.96 Å)

NMR 57 5 29 18 9 47 2

3DEM

(resolution)

223

(2.94‐50  Å)

4

(3.4–3.51 Å)

112

(2.95‐50 Å)

98

(2.94–8.5 Å)

20

(3.04–6.6 Å)

203

(2.94‐50 Å)

45

(3.8–16.5 Å)

Electron crystallography

(resolution)

3

(3.54–3.8 Å)

3

(3.54–3.8 Å)

0

3

(3.54–3.8 Å)

0

3

(3.54–3.8 Å)

0
Unique genes 84 8 45 24 11 69 5
a

N.B.: PDB structures may appear in multiple LGIC classification categories.

Note: Table generated in July 2019 based on gene ontology or GO#0015276.

Abbreviations: 3DEM, three‐dimensional electron microscopy; MX, macromolecular X‐ray crystallography; NMR, nuclear magnetic resonance.