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CABLAM markup as a guide to rebuilding regions poorly fitting into density: (a) shows a CaBLAM outlier in the 99–104 loop of the 1de9 DNA‐complex crystal structure at 3.1 Å,53 and (b) shows the rebuilt region fitting into density. (c) Indicates a missing residue by misalignment and poor fit of a loop in the alcohol dehydrogenase target at 2.9 Å in the 2019 CryoEM Challenge, and (d) shows a different, correct Challenge model which has the sequence aligned correctly and no outliers
