Table 2.
Incident rates of gastrointestinal bleeding among systemic sclerosis and control groups
| Systemic sclerosis (n = 3665) | Controls (n = 18,325) | ||||
|---|---|---|---|---|---|
| Clinical outcome | No. | Incidence ratea (95% CI) | No. | Incidence ratea (95% CI) | Incidence rate ratio (95% CI) |
| All gastrointestinal bleeding | 191 | 976.37 (847.27–1125.137) | 675 | 410.76 (380.91–442.95) | 2.38 (2.02–2.79) |
| Upper gastrointestinal bleeding | 117 | 591.75 (493.68–709.30) | 473 | 286.89 (262.17–313.94) | 2.06 (1.68–2.53) |
| Peptic ulcer bleeding | 84 | 422.96 (341.53–523.81) | 393 | 238.01 (215.60–262.74) | 1.78 (1.40–2.25) |
| Non-peptic ulcer bleeding | 101 | 507.83 (417.85–617.19) | 281 | 169.46 (150.76–190.48) | 3.00 (2.39–3.76) |
| Lower gastrointestinal bleeding | 105 | 528.20 (436.24–639.53) | 277 | 167.06 (148.50–187.94) | 3.16 (2.53–3.96) |
aIncidence of gastrointestinal bleeding: per 100,000 person-years