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. 2019 Dec 26;16:27. doi: 10.1186/s12950-019-0232-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — NGF suppressed the expression of pro-inflammatory mediators in HCECs exposed to poly (I:C) stimulation. a-d Real time RT-PCR analysis of mRNA levels in HCECs after exposure to poly (I:C) (25 μg/ml) in absence or presence of NGF treatment (50 ng/ml) for 18 h. NGF (50 ng/ml) suppressed the gene expression of pro-inflammatory mediators including IFNβ, MIP1α, MIP1β and RANTES in HCECs treated with 25 μg/ml poly (I:C). Data represented mean ± SD from three independent representative experiments in each condition