Table 3.

Anatomical regions with significant differences among MCI ε4–/–, MCI ε4+/−, MCI ε4+/+ patients and control subjects in voxel-based morphometry analysis.

Area	Coordinates*			Cluster extent	Z-score
	x	y	z
Right hippocampus	−18	−7.5	−12	588	5.48
Left hippocampus	27	−12	−15	458	5.33
Right parahippocampal gyrus	24	−33	−1.5	217	5.05
Left parahippocampal gyrus	−20	−36	3	128	4.92
Right thalamus	8	−22.5	8.1	235	5.10
Left thalamus	−3	−13.5	3	221	5.11
Right middle frontal gyrus	45	38	22	61	5.04
Left middle frontal gyrus	−32	56	−10	64	5.43
Right middle temporal gyrus	62	−12	−9	107	5.33

Significance was based on p < 0.05 family-wise error corrected.

^*Coordinates are in Montreal Neurological Institute space.