Table 1.
Differential metabolites between the groups using VIP ≥ 1 and Corr. Coeffs. at p < 0.05.
| Class | Name | HMDBID | KeggID | VIP | Corr. Coeffs. | P |
|---|---|---|---|---|---|---|
| Amino Acid | Allantoic acid | HMDB01209 | C00499 | 2.0 | 0.65 | 6.5e-03 |
| Methylcysteine | HMDB02108 | NA | 1.6 | −0.53 | 3.5e-02 | |
| Ratio of urea/allantoic acid | HMDB00294/HMDB01209 | C00086/C00499 | 1.7 | −0.56 | 2.5e-02 | |
| Gamma-aminobutyric acid | HMDB00112 | C00334 | 1.8 | −0.58 | 1.9e-02 | |
| Beta-alanine | HMDB00056 | C00099 | 2.1 | −0.67 | 4.3e-03 | |
| Aminoadipic acid | HMDB00510 | C00956 | 2.2 | −0.73 | 1.3e-03 | |
| Carbohydrates | Alpha-lactose | HMDB00186 | C00243 | 2.2 | 0.7 | 2.4e-03 |
| Glucose 6-phosphate | HMDB01401 | C00092 | 1.7 | 0.54 | 2.9e-02 | |
| D-Threitol | HMDB04136 | C16884 | 1.7 | 0.54 | 3.0e-02 | |
| D-Xylitol | HMDB02917 | C00379 | 1.5 | −0.5 | 5.0e-02 | |
| Sorbitol | HMDB00247 | C00794 | 1.7 | −0.54 | 3.2e-02 | |
| D-Ribose | HMDB00283 | C00121 | 1.7 | −0.56 | 2.5e-02 | |
| L-Sorbose | HMDB01266 | C08356 | 1.9 | −0.6 | 1.3e-02 | |
| Fatty Acids | Linoleic acid | HMDB00673 | C01595 | 1.6 | −0.53 | 3.4e-02 |
| Caproic acid | HMDB00535 | C01585 | 1.6 | −0.53 | 3.5e-02 | |
| Docosahexaenoic acid | HMDB02183 | C06429 | 1.6 | −0.53 | 3.5e-02 | |
| Myristic acid | HMDB00806 | C06424 | 1.8 | −0.6 | 1.4e-02 | |
| Behenic acid | HMDB00944 | C08281 | 2.4 | −0.78 | 3.2e-04 | |
| Nucleotide | Ratio of uridine/cytidine | HMDB00296/HMDB00089 | C00299/C00475 | 1.7 | 0.54 | 3e-02 |
| Organic acids | Taurine | HMDB00251 | C00245 | 2.1 | 0.68 | 3.8e-03 |
| Ratio of hypotaurine/3-sulfinato-L-alaninate | HMDB00965/HMDB60179 | C00519/C00606 | 1.5 | −0.5 | 4.8e-02 | |
| Glutaric acid | HMDB00661 | C00489 | 1.5 | −0.5 | 5.0e-02 | |
| L-pipecolic acid | HMDB00716 | C00408 | 1.7 | −0.54 | 3.0e-02 | |
| Uric acid | HMDB00289 | C00366 | 2.2 | −0.72 | 1.6e-03 | |
| Ratio of uric acid/xanthine | HMDB00289/HMDB00292 | C00366/C00385 | 2.2 | −0.72 | 1.8e-03 | |
| Vitamin | Pantothenic acid | HMDB00210 | C00864 | 1.9 | −0.6 | 1.3e-02 |
VIP, variable importance in the projection; KEGG ID, ID in the Kyoto Encyclopedia of Genes and Genomes; HMDBID, ID in the Human Metabolome Database; Corr. Coeffs., correlation coefficient.