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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2019 Oct 12;29(12):1343–1353. doi: 10.1016/j.euroneuro.2019.09.009

Fig. 2. α7 nAChR full agonist PNU282987 (1 mg/kg i.p.) produced an anti-immobility effect in the FST only in those rats exposed to chronic mild stress.

Fig. 2.

(A) Body weight of CMS and control rats over the five weeks of experiment (n = 30–32 rats/group). (B) Total immobility time in the first session of forced swim (n = 30–32 rats/group). Students t test: *p=0.042. (C) Immobility development across time in the first session of forced swim (n = 30–32 rats/group). Bonferroni post-hoc test: *p=0.038. (D) Total distance travelled (cm) during a 5 min open field task (n=15–16 rats/group). (E) Immobility time in the second forced swim session (n=15–16 rats/group). Bonferroni post-hoc test: ***p<0.001 comparing with control+vehicle, ##p<0.01 comparing with CMS+vehicle. Data are expressed as mean ± S.E.M.