Table 2.
Clusters demonstrating a significant relationship between mental health symptoms and BOLD activation of parent or adolescent while processing a costly error committed by their dyadic partner (voxel-wise p < 0.005).
| Symptom Measure | Regions in Cluster | L/R | Vol (mm3) | x | y | z | t-value | η2G | p-value | BA |
|---|---|---|---|---|---|---|---|---|---|---|
| Parent BOLD Activation | ||||||||||
| Adolescent Depression (MFQ) | Posterior Cingulate, Precuneus, Cuneus | Bilateral | 2936 | −6 | −61 | 32 | −5.61 | 0.60 | < 0.01 | 7, 23, 29, 30, 31 |
| Adolescent Anxiety (SCARED) | Posterior Cingulate, Precuneus, Cuneus | Bilateral | 2213 | −10 | −55 | 21 | −5.30 | 0.58 | 0.02 | 7, 23, 29, 30, 31 |
| Adolescent Anxiety (SCARED) | Medial Frontal Gyrus, Anterior Cingulate | L | 488 | −8 | 39 | 23 | −5.34 | 0.59 | 0.03 | 9, 32 |
| Parent Depression (QIDS) | Dorsolateral Prefrontal Cortex | L | 595 | −29 | 3 | 51 | 5.11 | 0.54 | 0.02 | 6 |
| Adolescent BOLD Activation | ||||||||||
| Parent Anxiety (HAM-A) | Anterior Insula | L | 188 | −45 | 11 | 4 | 4.53 | 0.48 | 0.05 | 13, 44 |
Note. MFQ = Mood and Feelings Questionnaire. SCARED = Screen for Child Anxiety Related Disorders. QIDS = Quick Inventory of Depressive Symptomatology. HAM-A = Hamilton Anxiety Rating Scale. L = left hemisphere. Vol = Volume in cubic millimeters. Talairach coordinates and t-value reflect the area of peak activation in the cluster. η2G = Generalized Eta-Squared, which should be interpreted with caution due to possible inflation (Yarkoni, 2009). p-value = Minimum cluster-wise threshold. BA = Brodmann Area gathered from the 'whereami' function in AFNI.