Table 3.

Prognostic Factors in Univariate and Multivariate Analyses of RFS

Variable	Univariate Analysis		Multivariate Analysis
HR (95% CI)	P value	HR (95% CI)	P value
Age
≥ 60 vs < 60	0.844(0.551–1.293)	0.968
Gender
Male vs female	0.705(0.423–1.117)	0.436
HBsAg
Negative vs positive	0.977(0.869–1.097)	0.692
AST(U/L)
>40 vs ≤40	1.417(1.041–1.930)	0.027	1.012(0.726–1.409)	0.946
ALT (U/L)
>40 vs ≤40	1.217(0.893–1.695)	0.214
GGT (U/L)
>75 vs ≤75	2.228(1.634–3.038)	<0.001	1.855(1.332–2.582)	<0.001
ALP (U/L)
>110 vs ≤110	1.580(0.833–2.995)	0.161
Albumin (g/L)
>40 vs≤40	0.571(0.42–0.778)	<0.001	0.697(0.500–0.971)	0.033
TB (umol/L)
>17.1 vs≤17.1	0.977(0.814–1.174)	0.807
AFP (ng/dL)
> 400 vs ≤400	1.000(1.000–1.000)	0.408
PLT(109/L)
> 100 vs ≤100	1.001(0.999–1.003)	0.357
Child-pugh grade
Grade A or B	1.320(0.647–2.691)	0.445
Ascites
Yes vs no	1.548(1.150–2.086)	0.004	1.375(1.024–1.845)	0.034
Liver cirrhosis
Yes vs no	0.784(0.555–1.107)	0.167
Lymph node metastasis
Yes vs no	1.041(0.591–1.835)	0.888
Portal vein tumor thrombus
Yes vs no	2.690(1.830–3.955)	<0.001	1.735(1.082–2.784)	0.022
Tumor number
Multiple vs single	1.703(1.261–2.299)	0.001	1.578(1.161–2.144)	0.004
Tumor size (cm)
>5 vs ≤5	1.629(1.198–2.216)	0.002	1.226(0.884–1.700)	0.223
TNM
I+II or III + IV	2.397(1.725–3.330)	<0.001	1.410(0.938–2.118)	0.098