Table 1.
Baseline Demographics And Characteristics (Safety Analysis Set)
| Characteristics | Total (n=130) | Osteoarthritis (n=56) | Diabetic Neuropathic Pain (n=11) | Post-Herpetic Neuralgia (n=28) | Other Chronic Pain Conditions (n=35) |
|---|---|---|---|---|---|
| Age, 65 to <80 years, n (%) | 73 (56.2) | 28 (50.0) | 8 (72.7) | 26 (92.9) | 11 (31.4) |
| Age, years, mean±SD | 63.6±11.3 | 63.6±9.4 | 65.1±10.4 | 72.6±4.9 | 55.9±12.9 |
| Sex, female, n (%) | 81 (62.3) | 42 (75.0) | 4 (36.4) | 16 (57.1) | 19 (54.3) |
| Outpatient, n (%) | 128 (98.5) | 56 (100.0) | 10 (90.9) | 28 (100.0) | 34 (97.1) |
| Height, cm, mean±SD | 158.0±10.0 | 157.7±7.7 | 158.8±7.4 | 157.4±9.4 | 158.7±14.1 |
| Weight, kg, mean±SD | 61.9±11.7 | 64.6±11.5 | 64.5±13.2 | 56.9±10.2 | 60.3±11.8 |
| Prior opioid analgesics, n (%) | |||||
| Morphine | 5 (3.8) | 0 | 0 | 2 (7.1) | 3 (8.6) |
| Codeine | 4 (3.1) | 0 | 1 (9.1) | 3 (10.7) | 0 |
| Fentanyl | 23 (17.7) | 4 (7.1) | 0 | 8 (28.6) | 11 (31.4) |
| Buprenorphine | 2 (1.5) | 1 (1.8) | 0 | 0 | 1 (2.9) |
| Tramadol | 67 (51.5) | 44 (78.6) | 1 (9.1) | 10 (35.7) | 12 (34.3) |
| No opioid analgesics | 29 (22.3) | 7 (12.5) | 9 (81.8) | 5 (17.9) | 8 (22.9) |
| Significant previous medical condition, n (%) | 8 (6.2) | 2 (3.6) | 4 (36.4) | 2 (7.1) | 0 |
| Comorbidities, n (%) | 124 (95.4) | 51 (91.1) | 11 (100.0) | 28 (100.0) | 34 (97.1) |
Abbreviation: SD, standard deviation.