Table 3.
Pathological Characteristics | n | MMP-2 | MMP-9 | TIMP-1 | TIMP-2 | |
---|---|---|---|---|---|---|
(ng/mL) | (ng/mL) | (ng/mL) | (ng/mL) | |||
TNM | Phase I | 17 | 80.14±17.30 | 108.43±21.30 | 78.44±20.37 | 62.23±21.52 |
Phase II, III | 40 | 140.57±32.30a | 157.20±24.58a | 130.27±28.43a | 102.17±23.38a | |
Tumor size | <1.0 cm | 10 | 76.54±20.32 | 90.28±26.30 | 86.27±20.30 | 60.49±21.30 |
≥1.0 cm | 47 | 143.27±27.54b | 148.24±31.46b | 140.42±28.19b | 112.20±29.58b | |
Extent of infiltration | Limited to the thyroid | 41 | 75.24±25.37 | 101.27±25.32 | 102.63±20.49 | 58.47±23.57 |
Outside the thyroid | 16 | 147.19±26.33c | 156.36±17.54c | 154.24±26.50c | 119.43±19.35c | |
Lymph metastasis | No | 37 | 81.46±20.39 | 91.20±21.52 | 100.20±20.73 | 59.71±16.33 |
Yes | 20 | 152.28±24.62d | 150.98±26.74d | 152.23±21.27d | 120.20±22.36d |
Notes: aCompared with Phase I, P<0.05. bCompared with patients with tumor size <1.0 cm, P<0.05. cCompared with patients with tumor limit in thyroid, P<0.05. dCompared with patients without lymph metastasis, P<0.05.