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. 2019 Dec 23;11:10675–10681. doi: 10.2147/CMAR.S233776

Table 3.

Clinicopathological Features of DTC and the Levels of MMPs and TIMPs in Peripheral BloodInline graphic)

Pathological Characteristics n MMP-2 MMP-9 TIMP-1 TIMP-2
(ng/mL) (ng/mL) (ng/mL) (ng/mL)
TNM Phase I 17 80.14±17.30 108.43±21.30 78.44±20.37 62.23±21.52
Phase II, III 40 140.57±32.30a 157.20±24.58a 130.27±28.43a 102.17±23.38a
Tumor size <1.0 cm 10 76.54±20.32 90.28±26.30 86.27±20.30 60.49±21.30
≥1.0 cm 47 143.27±27.54b 148.24±31.46b 140.42±28.19b 112.20±29.58b
Extent of infiltration Limited to the thyroid 41 75.24±25.37 101.27±25.32 102.63±20.49 58.47±23.57
Outside the thyroid 16 147.19±26.33c 156.36±17.54c 154.24±26.50c 119.43±19.35c
Lymph metastasis No 37 81.46±20.39 91.20±21.52 100.20±20.73 59.71±16.33
Yes 20 152.28±24.62d 150.98±26.74d 152.23±21.27d 120.20±22.36d

Notes: aCompared with Phase I, P<0.05. bCompared with patients with tumor size <1.0 cm, P<0.05. cCompared with patients with tumor limit in thyroid, P<0.05. dCompared with patients without lymph metastasis, P<0.05.