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. 2019 Dec 23;11:10705–10718. doi: 10.2147/CMAR.S214614

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© 2019 Ma et al.

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Identification of SE-associated hub genes in CML patients and K562 cells. (A) Boxplots showing mRNA expression of SE-associated hub genes in CML patient groups (CP, AP, and BP) (GSE), compared to the control group. Differences were considered significant at p-values < 0.05 (*). Compared to different phase groups, p-values < 0.05 were considered significant (#). (B) Boxplots and dotplots showing mRNA expression of SE-associated hub genes in CML patients from Xiangya Hospital. Differences were considered significant at p-values < 0.05 (*), compared to the control group. (C and D) mRNA and protein levels of SE-associated genes in K562 cells after treatment with JQ1 (1 and 10 μM). Differences were considered significant at p-values < 0.05 (*), compared to the control group.