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. 2019 Dec 20;10:3004. doi: 10.3389/fimmu.2019.03004

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Copyright © 2019 Roerden, Nelde and Walz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Origins of neoantigens. Schematic overview showing different origins of neoantigens with prominent examples in hematological malignancies. AML, acute myeloid leukemia; FLT3, FMS like tyrosine kinase 3; HLA, human leukocyte antigen; NPM1, nucleophosmin 1; IDH, isocitrate dehydrogenase; MPN, myeloproliferative neoplasia; CALR, calreticulin; JAK2 janus like kinase 2; CML, chronic myeloid leukemia; CLL, chronic lymphocytic leukemia; MCL, mantle cell lymphoma; Ig, immunoglobulin.