Table 5.

Multivariable Logistic Regression Model for Clinical Failure^a

Variable	Adjusted Odds Ratio (95% CI)	P Value
Primary bacteremia or respiratory tract infection	2.270 (1.115–4.620)	<.001
SOFA score	1.234 (1.118–1.362)	.0238
CZA within 48 hours of culture collection	0.409 (0.180–0.930)	.0329

Abbreviations: CI, confidence interval; CZA, ceftzidime-avibactam; SOFA, Sequential Organ Failure Assessment.

^aVariable considered for model entry were as follows: admission from an outside hospital, creatinine clearance ≤30 mL/min or receipt of hemodialysis, previous hospitalization within 90 days, hospital-acquired infection, primary bacteremia or respiratory tract infection, pursuit of source control, early (≤48 hours) active antibiotic therapy, early (≤48 hours) CZA, Acute Physiological and Chronic Health Evaluation (APACHE) II score, SOFA score, intensive care unit at infection onset.