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. 2019 Dec 9;130(1):539–551. doi: 10.1172/JCI131958

Figure 7. Immunohistochemistry.

Figure 7

Images of liver of representative control macaques (A, C, E, and G) showing diffuse cytoplasmic immunolabeling (brown color) of sinusoidal lining cells, Kupffer cells, and rare hepatocytes of animals infected with LASV (A), EBOV (C), SUDV (E), and MARV (G). No immunolabeling was detected in liver of specifically vaccinated macaques that survived virus challenge, as shown by representative animals exposed to LASV (B), EBOV (D), SUDV (F), or MARV (H). All representative images taken at ×20.