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. 2019 Dec 27;14(12):e0226992. doi: 10.1371/journal.pone.0226992

Table 3. Logistic regression analyses for clinical and sociodemographic correlates with normal and abnormal menstruation in the last 6 months in Canadian women living with HIV in CHIWOS cohort (n = 521).

Variable Unadjusted Adjusted
  OR (95%CI) P-value OR (95%CI) P-value
Age at Interview Date 1.04 (1.01, 1.08) 0.006 1.03 (1.00, 1.07) 0.07
Duration of HIV Infection (months) 1.004 (1.001, 1.007) 0.003 1.002 (0.999, 1.005) 0.147
Biological Mother/Sister who entered natural menopause before age 40 <0.001 0.001
    No 1.00 (-) 1.00 (-) <0.001
    Yes 7.46 (2.19, 25.37) 5.01 (1.39, 18.03)
Don’t Know 3.05 (1.80, 5.16) 2.53 (1.44, 4.45)
Most Recent CD4 0.232 Not Selected
    <350 1.00 (-)
    > = 350 0.65 (0.35, 1.21)
Does not know 0.56 (0.28, 1.09)
Cigarette use <0.001 0.017
    Never 1.00 (-) 1.00 (-)
    Former 0.96 (0.47, 1.93) 0.61 (0.27, 1.40)
    Current 2.30 (1.55, 3.41) 1.69 (1.06, 2.68)
Injection drug use <0.001 Not Selected
    Never 1.00 (-)
    Previous use 2.88 (1.70, 4.90)
    Current use 4.53 (1.94, 10.57)
Hepatitis B 0.008 0.012
    No 1.00 (-) 1.00 (-)
    Yes 7.38 (1.69, 32.20) 6.97 (1.52, 31.88)
Hepatitis C <0.001 Not Selected
    No 1.00 (-)
    Yes 2.55 (1.62, 4.01)
ART use <0.001 0.030
    Never on ARTs 1.00 (-) 1.00 (-)
    Previous ART 3.90 (1.39, 10.95) 2.11 (0.67, 6.43)
    Currently on ART 4.20 (2.41, 7.33) 2.36 (1.25, 4.45)
Province Interview Conducted <0.001 0.001
    Ontario 1.00 (-) 1.00 (-)
    British Columbia 4.83 (2.84, 8.21) 2.95 (1.61, 5.39)
    Quebec 2.26 (1.42, 3.60)   1.9 (1.13, 3.09)  
Household gross yearly income 0.040 0.061
    $20 000 or more 1.00 (-) 1.00 (-)
    < $20 000 1.49 (1.02, 2.17) 1.52 (0.98, 2.37)
Education 0.003 Not Selected
    Less than high school 1.00 (-)
    High school or greater 0.38 (0.20, 0.71)
Food Security 0.151 Not Selected
    Sufficient 1.00 (-)
    Insufficient 1.37 (0.89, 2.11)

ART, antiretroviral therapy, VL, viral load