Figure 6.
Triad combination (colistin + salicylate + BC1) effectively reduces bacterial bioburden in infected zebrafish. 105 CFU/ml of U3790 was injected intramuscularly in zebrafish. Different treatment combinations were administered 2–3 h post-infection. The zebrafish were sacrificed after 48 h and the colony counts (CFU/ml) from dissected muscle tissue was determined by plating the samples on agar plates. Experiment was performed in triplicates and statistical analyses were performed using Student’s t-test.