Table 2.
Bone mineral density and bone microstructure of each group at postoperative 4 weeks.
| parameter | (unit) | group W; CIA(−) P.g(−) | group P; CIA(+) P.g(−) | group C; CIA(+) P.g(−) | group PC; CIA(+) P.g(+) |
|---|---|---|---|---|---|
| TV | (mm3) | 1.13 ± 0.06 | 1.04 ± 0.02 | 1.13 ± 0.06 | 1.09 ± 0.05 |
| BV | (mm3) | 0.17 ± 0.02 | 0.11 ± 0.01 | 0.10 ± 0.01 | 0.07 ± 0.01*, ## |
| BV/TV | (%) | 14.5 ± 1.27 | 10.8 ± 0.66 | 8.16 ± 0.46* | 6.40 ± 0.42**, ## |
| Tb.Th | (µm) | 58.9 ± 2.58 | 58.2 ± 1.81 | 48.5 ± 3.06 | 51.8 ± 3.44 |
| Tb.N | (1/mm) | 1.52 ± 0.10 | 1.13 ± 0.04* | 1.17 ± 0.05 | 0.88 ± 0.06**, #, $ |
| Tb.Sp | (µm) | 162 ± 8.23 | 185 ± 9.96 | 190 ± 6.71 | 203 ± 11.3* |
| Tb.Spac | (µm) | 220 ± 8.35 | 243 ± 9.46 | 238 ± 7.70 | 254 ± 12.0 |
| TMD | (mg/cm3) | 750 ± 49.0 | 592 ± 44.7 | 499 ± 19.2** | 485 ± 18.6** |
| vBMD | (mg/cm3) | 107 ± 9.18 | 64.7 ± 5.46* | 40.6 ± 2.47** | 30.7 ± 1.59**, #, $ |
Data are expressed as mean ± SEM, n = 6–8/group. CIA(+) or (−); with or without collagen-induced arthritis, P.g(+) or (−); with or without P. gingivalis administration, TV; tissue volume, BV; bone volume, BS; bone surface, Tb.Th; trabecular thickness, Tb.N; trabecular number, Tb.sp; trabecular separation, Tb.spac; trabecular spacing, TMD; tissue mineral density, vBMD; volumetric bone mineral density, *P < 0.05, **P < 0.01 compared with the group W, #P < 0.05, ##P < 0.01 compared with the group P, $P < 0.05 compared with the group C.