Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 27;9:20194. doi: 10.1038/s41598-019-56651-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Induced pluripotent stem cells (iPSCs) cultivated in apple-derived scaffolds: (A) Drawings of various plant scaffolds showing shape and pore sizes; (B–D) Pore sizes, cell proliferation assay (CCK-8), and scanning electron microscopic images of human induced pluripotent stem cells (hiPSCs) seeded in apple scaffolds; (E) Phase contrast (top) and haematoxylin & eosin-stained (bottom) images of hiPSCs seeded onto apple scaffolds (original magnifications: 100x and 200x); (F) Views of live and dead cells in cultures after 48 h (top panels) and 96 h (bottom panels); (G) Proportion of the live and dead cells in cultures after 48 h and 96 h; (H) mRNA expression levels of iPSC markers in control iPSCs and iPSCs cultured in apple scaffolding; (I) Immunofluorescence staining of iPSC markers in iPSCs cultured in apple scaffolding; and (J) mRNA expression levels of LIN28 and OCT3/4 in control iPSCs and iPSCs cultured in apple scaffolding (*p < 0.01; **p < 0.005; and ***p < 0.001).