Table 4.
Results of GO function and KEGG pathway enrichment analyses.
| Category | Term | Count of genes | P-value |
|---|---|---|---|
| GO biology process | Cytokine-mediated signaling pathway | 8 | 2.70 × 10−4 |
| Positive regulation of cell migration | 8 | 2.00 × 10−3 | |
| Negative regulation of angiogenesis | 5 | 2.95 × 10−3 | |
| Negative chemotaxis | 4 | 4.16 × 10−3 | |
| Establishment of skin barrier | 3 | 1.26 × 10−2 | |
| Melanocyte differentiation | 3 | 1.55 × 10−2 | |
| Signal transduction | 20 | 1.56 × 10−2 | |
| Thyroid gland development | 3 | 2.37 × 10−2 | |
| Mesenchymal-epithelial cell signaling | 2 | 2.85 × 10−2 | |
| Cornification | 2 | 2.85 × 10−2 | |
| Transcription, DNA-templated | 28 | 3.24 × 10−2 | |
| Positive regulation of inflammatory response | 4 | 3.30 × 10−2 | |
| Wnt signaling pathway | 6 | 3.43 × 10−2 | |
| Blood vessel remodeling | 3 | 3.76 × 10−2 | |
| Lung alveolus development | 3 | 4.20 × 10−2 | |
| Regulation of cell shape | 5 | 4.59 × 10−2 | |
| Positive regulation of glucose transport | 2 | 4.70 × 10−2 | |
| Negative regulation of cell cycle | 3 | 4.89 × 10−2 | |
| KEGG pathway | cGMP-PKG signaling pathway | 7 | 5.21 × 10−3 |
| Gastric acid secretion | 5 | 6.31 × 10−3 | |
| Vascular smooth muscle contraction | 6 | 6.56 × 10−3 | |
| Inflammatory mediator regulation of TRP channels | 5 | 1.73 × 10−2 | |
| Estrogen signaling pathway | 5 | 1.79 × 10−2 | |
| Pathways in cancer | 9 | 4.50 × 10−2 | |
| Aldosterone synthesis and secretion | 4 | 4.90 × 10−2 |
GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.