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. 2019 Dec 27;9:20157. doi: 10.1038/s41598-019-56601-w

Table 6.

Multivariable linear regression analyses with changes in serum levels of 10 markers, PSG parameters and biomarker levels.

ΔAHI ΔMean SaO2 ΔLSpO2 ΔCT90% ΔODI ΔMAI ΔESS ΔGlucose ΔHOMA-IR ΔTC ΔLDL-C ΔApoB
ΔVEGFA 0.001 6.334 0.423 1.071* 0.142 −0.131 −0.817 13.406* −1.859 9.299 −25 −52.019
ΔAng2 −0.004 −0.009 −0.007 −0.007* 0.008* −0.003 0.014 −0.069* 0.009 −0.013 0.033 0.896*
ΔE-selectin 0.02 0.23 −0.41 −2.649 5.112 −0.008 0.319 39.159 −9.695 −0.886 −4.8 101.277
ΔvWF 1.073 −11.994 −3.123 −5.123 0.399 −0.669 2.951 −9.962 −9.847 45.051 −4.8 −260.24
ΔvWFCP −4.076 −8.073 −0.41 −2.649 5.112 −0.008 0.319 39.159 −9.695 −0.886 −30.332 101.277
ΔTM 0.001 0.01 0.003 0.005 −0.001 0 −0.001 −0.005 −0.006 0.038 −0.001 −0.087

Abbreviations: VEGFA = vascular endothelium growth factor A, Ang2 = angiopoietin-2, E-selectin = endothelial-leukocyte adhesion molecule, vWF = von willebrand factor, vWFCP = von willebrand factor cleavage protease, TM = thrombomodulin, AHI = apnea-hypopnea index, SaO2 = oxygen saturation, LSpO2 = lowest pulse oxygen saturation, CT90 = percentage of time during which oxyhemoglobin saturation was < 90%, ODI = oxygen desaturation index, MAI = micro-arousal index, ESS = Epworth Sleepiness Scale, HOMA-IR = homeostasis model of assessment for insulin resistance index, TC = total cholesterol, LDL-C = low-density lipoprotein cholesterol, Apo B = apolipoprotein B.

*p < 0.05.