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. 2019 Dec 27;9:19961. doi: 10.1038/s41598-019-56509-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differentially expressed genes (DEGs) between peritumoral brain and GBM tissue. Analysis of differentially expressed genes (DEGs) between untreated peritumoral brain tissue of zone III and GBM tissue samples of zone I (a–c) and between untreated and treated GBM samples (d–f). (a,d) Significantly regulated transcripts are indicated in red (p < 0.01). (b,e) Number of down- and upregulated genes in both comparisons. (c,f) Biotype of down- (red) and upregulated (blue) transcripts in both comparisons. TEC = to be experimentally confirmed, NA = not available.