Table 2.

Top diseases and functions of significant differentially expressed genes in untreated peritumoral brain vs. GBM tissue.

Diseases and disorders	p-value	molecules of 3280 in total
Cancer	1.64 × 10−09 − 1.29 × 10−150	3101
- Tumorigenesis of tissue	3.29 × 10−145	3040
- Malignant solid tumor	1.90 × 10−139	3084
Organismal injury and abnormalities	1.64 × 10−09 − 1.29 × 10−150	3135
Gastrointestinal disease	8.04 × 10−10 − 1.88 × 10−130	2822
Endocrine disorders	1.47 × 10−09 − 3.03 × 10−112	2641
Dermatological diseases and conditions	6.23 × 10−11 − 3.08 × 10−90	1926
Molecular and cellular functions
Cellular development	9.97 × 10−10 − 1.91 × 10−44	598
Cellular growth and proliferation	9.97 × 10−10 − 1.91 × 10−44	511
- Proliferation of neuronal cells	3.25 × 10−15	198
Cellular assembly and organization	4.76 × 10−10 − 1.90 × 10−41	747
Cellular function and maintenance	9.97 × 10−10 − 1.90 × 10−41	973
Cell-to-cell signaling and interaction	1.65 × 10−09 − 1.60 × 10−37	677
Physiological system development and function
Nervous system development and function	1.65 × 10−09 − 1.91 × 10−44	994
Tissue development	1.65 × 10−09 − 1.91 × 10−44	999
Embryonic development	1.61 × 10−09 − 8.66 × 10−40	768
Organismal development	1.65 × 10−09 − 8.66 × 10−40	1198
Tissue morphology	1.61 × 10−09 − 7.98 × 10−33	804