Table 2.
Top diseases and functions of significant differentially expressed genes in untreated peritumoral brain vs. GBM tissue.
| Diseases and disorders | p-value | molecules of 3280 in total |
|---|---|---|
| Cancer | 1.64 × 10−09 − 1.29 × 10−150 | 3101 |
| - Tumorigenesis of tissue | 3.29 × 10−145 | 3040 |
| - Malignant solid tumor | 1.90 × 10−139 | 3084 |
| Organismal injury and abnormalities | 1.64 × 10−09 − 1.29 × 10−150 | 3135 |
| Gastrointestinal disease | 8.04 × 10−10 − 1.88 × 10−130 | 2822 |
| Endocrine disorders | 1.47 × 10−09 − 3.03 × 10−112 | 2641 |
| Dermatological diseases and conditions | 6.23 × 10−11 − 3.08 × 10−90 | 1926 |
| Molecular and cellular functions | ||
| Cellular development | 9.97 × 10−10 − 1.91 × 10−44 | 598 |
| Cellular growth and proliferation | 9.97 × 10−10 − 1.91 × 10−44 | 511 |
| - Proliferation of neuronal cells | 3.25 × 10−15 | 198 |
| Cellular assembly and organization | 4.76 × 10−10 − 1.90 × 10−41 | 747 |
| Cellular function and maintenance | 9.97 × 10−10 − 1.90 × 10−41 | 973 |
| Cell-to-cell signaling and interaction | 1.65 × 10−09 − 1.60 × 10−37 | 677 |
| Physiological system development and function | ||
| Nervous system development and function | 1.65 × 10−09 − 1.91 × 10−44 | 994 |
| Tissue development | 1.65 × 10−09 − 1.91 × 10−44 | 999 |
| Embryonic development | 1.61 × 10−09 − 8.66 × 10−40 | 768 |
| Organismal development | 1.65 × 10−09 − 8.66 × 10−40 | 1198 |
| Tissue morphology | 1.61 × 10−09 − 7.98 × 10−33 | 804 |