Table 2.
Comparison between the Cnm-positive and Cnm-negative IgAN patients.
| Characteristics | Cnm-positive (n = 15) | Cnm-negative (n = 46) | p-value |
|---|---|---|---|
| Age (year; mean ± SD) | 39.0 (32.1–45.9) | 34.9 (31.5–38.3) | 0.2650 |
| Sex (M/F) | 9/6 | 22/24 | 0.5541 |
| Duration from onset to treatment (year; mean ± SD) | 5.2 ± 5.4 | 7.5 ± 9.4 | 0.9112 |
| BMI (kg/m2; mean ± SD) | 23.5 ± 5.9 | 21.3 ± 2.7 | 0.4754 |
| Systolic blood pressure (mmHg; mean ± SD) | 116.6 ± 17.1 | 117.8 ± 17.7 | 0.6817 |
| Diastolic blood pressure (mmHg; mean ± SD) | 70.0 ± 12.5 | 70.8 ± 13.4 | 0.7779 |
| Serum albumin (g/dL; mean ± SD) | 3.8 ± 0.4 | 4.1 ± 0.3 | 0.0256 |
| Serum total cholesterol (mg/dL; mean ± SD) | 216.7 ± 82.2 | 193.3 ± 28.9 | 0.5082 |
| Serum LDL cholesterol (mg/dL; mean ± SD) | 140.1 ± 83.7 | 111.9 ± 22.7 | 0.3461 |
| Serum triglyceride (mg/dL; mean ± SD) | 179.2 ± 167.7 | 104.8 ± 58.3 | 0.0789 |
| Serum creatinine (mg/dL; mean ± SD) | 0.8 ± 0.2 | 0.7 ± 0.1 | 0.1472 |
| eGFR (mL/min/1.73 m2; mean ± SD) | 75.5 ± 18.0 | 85.4 ± 19.5 | 0.1067 |
| Serum IgA (mg/dL; mean ± SD) | 350.1 ± 123.6 | 338.0 ± 117.9 | 0.4460 |
| % Urinary protein 1.5 g/gCr or higher | 26.6 | 4.3 | 0.0280 |
| Urinary RBC score (0~3; mean ± SD) | 2.1 ± 0.7 | 1.9 ± 0.8 | 0.4649 |
BMI: body mass index, eGFR: estimated glomerular filtration rate. SD: standard deviation,
RBC: red blood cell, LDL: low-density lipoprotein
Bold values indicate statistical significance at p < 0.05.