Table 2.
Biological pathways enriched in the bone mineral density Z score-associated common module.
| ID | Name† | Depth‡ | P value§ |
|---|---|---|---|
| GO:1903901 | Negative regulation of viral life cycle | 1 | 0.0418 |
| GO:0045071 | Negative regulation of viral genome replication | 1 | 0.014 |
| GO:0006475 | Internal protein amino acid acetylation | 1 | 0.0448 |
| GO:0018394 | Peptidyl-lysine acetylation | 1 | 0.0453 |
| GO:0018393 | Internal peptidyl-lysine acetylation | 2 | 0.0394 |
| GO:0018076 | N-terminal peptidyl-lysine acetylation | 2 | 0.0287 |
| GO:0016570 | Histone modification | 1 | 0.0291 |
| GO:0016573 | Histone acetylation | 2 | 0.0352 |
| GO:0010646 | Regulation of cell communication | 1 | 0.0485 |
| GO:0051169 | Nuclear transport | 1 | 0.041 |
| GO:0006913 | Nucleocytoplasmic transport | 2 | 0.0374 |
| GO:0002886 | Regulation of myeloid leukocyte mediated immunity | 1 | 0.0321 |
| GO:0002279 | Mast cell activation involved in immune response | 1 | 0.0453 |
| GO:0051640 | Organelle localization | 1 | 0.0335 |
| GO:0043300 | Regulation of leukocyte degranulation | 1 | 0.0336 |
| GO:0051656 | Establishment of organelle localization | 1 | 0.0052 |
| GO:0033003 | Regulation of mast cell activation | 1 | 0.0283 |
| GO:0033006 | Regulation of mast cell activation involved in immune response | 2 | 0.0153 |
| GO:0043303 | Mast cell degranulation | 1 | 0.0453 |
| GO:0043304 | Regulation of mast cell degranulation | 2 | 0.0153 |
| GO:0050657 | Nucleic acid transport | 1 | 0.0335 |
| GO:0051236 | Establishment of RNA localization | 1 | 0.0354 |
| GO:0050658 | RNA transport | 2 | 0.0335 |
| GO:0006405 | RNA export from nucleus | 3 | 0.0287 |
| GO:0071166 | Ribonucleoprotein complex localization | 1 | 0.0219 |
| GO:0071426 | Ribonucleoprotein complex export from nucleus | 2 | 0.0205 |
| GO:0008150 | Biological process | 1 | 0.00234 |
| GO:0071840 | Cellular component organization or biogenesis | 2 | 0.0279 |
| GO:0044085 | Cellular component biogenesis | 3 | 0.00104 |
| GO:0008152 | Metabolic process | 2 | 0.00000288 |
| GO:0044238 | Primary metabolic process | 3 | 0.000013 |
| GO:0071704 | Organic substance metabolic process | 3 | 0.0000188 |
| GO:0009058 | Biosynthetic process | 3 | 0.000516 |
| GO:0006807 | Nitrogen compound metabolic process | 3 | 0.0000273 |
| GO:0009987 | Cellular process | 2 | 0.000425 |
| GO:0044237 | Cellular metabolic process | 3 | 0.000000275 |
| GO:0043933 | Macromolecular complex subunit organization | 1 | 0.0278 |
| GO:0071822 | Protein complex subunit organization | 2 | 0.019 |
| GO:0065003 | Macromolecular complex assembly | 1 | 0.0289 |
| GO:0006461 | Protein complex assembly | 2 | 0.0278 |
| GO:0010629 | Negative regulation of gene expression | 1 | 0.0138 |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 1 | 0.0272 |
| GO:0002520 | Immune system development | 1 | 0.0138 |
| GO:0048534 | Hematopoietic or lymphoid organ development | 2 | 0.0167 |
| GO:0030097 | Hemopoiesis | 3 | 0.0225 |
| GO:0006325 | Chromatin organization | 1 | 0.034 |
| GO:0031648 | Protein destabilization | 1 | 0.0356 |
| GO:0033554 | Cellular response to stress | 1 | 0.00328 |
| GO:0036294 | Cellular response to decreased oxygen levels | 1 | 0.0448 |
| GO:0071456 | Cellular response to hypoxia | 2 | 0.038 |
| GO:0043618 | Regulation of transcription from RNA polymerase II promoter in response to stress | 1 | 0.0428 |
| GO:0061418 | Regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2 | 0.0466 |
| GO:0051649 | Establishment of localization in cell | 1 | 0.0302 |
†Gene ontology biological pathway, ‡Only depth 1~3 were presented, §Benjamini-Hocherg FDR P value.