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. 2019 Dec 27;9:19869. doi: 10.1038/s41598-019-56407-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Common Crebl2 targets in myoblast and hepatoma cells. (A) Overlap of Crebl2 dependent genes in C2C12 myoblasts and Hepa1–6 cells. Genes in bold italic were tested for their effect on TAG levels in (B). (B) Summary of 7 different experiments (3 in C2C12, 4 in Hepa1–6 cells) comparing TAG levels of cells treated for 3 days with control and Crebl2 siRNA #1. Control cells were normalized to 1 for each experiment in order to combine and compare multiple biological replicates. *p < 0.05, ^$p < 0.1 by one-sample two-tailed t-test with a hypothetical mean of 1.0.