Table 4.
No./Total(%) | 24–27 weeks (n = 148) | 28–31 weeks (n = 1612) | 32–33 weeks (n = 2460) | 34–36 weeks (n = 9481) | Total (N = 13701) | χ2 | p |
---|---|---|---|---|---|---|---|
Died | 47 (31.8) | 108 (6.7) | 45 (1.8) | 56 (0.6) | 256 (1.9) | 1010.711 | 0.000 |
Survived to dischargea | 101 (68.2) | 1504 (93.3) | 2415 (99.2) | 9425 (99.4) | 13445 (98.1) | 1010.711 | 0.000 |
Survived to discharge without major morbidityb | 64 (63.4) | 1246 (82.8) | 2227 (92.2) | 9137 (96.9) | 12674 (94.3) | 685.124 | 0.000 |
RDSa | 131 (88.5) | 900 (55.8) | 603 (24.5) | 512 (5.4) | 2146 (15.7) | 3465.331 | 0.000 |
RDS stage III+a | 50 (33.8) | 178 (11.0) | 115 (4.7) | 81 (0.9) | 424 (3.1) | 3688.745 | 0.000 |
BPDc | 29 (19.6) | 165 (10.2) | 37 (1.5) | 54 (0.6) | 285 (2.1) | 859.508 | 0.000 |
Moderate/severe BPDc | 15 (10.1) | 83 (5.1) | 21 (0.8) | 48 (0.5) | 167 (1.3) | 898.967 | 0.000 |
ICHc | 33 (22.3) | 227 (14.1) | 293 (11.9) | 639 (6.7) | 1192 (8.7) | 171.016 | 0.000 |
Severe IVHc | 6 (4.1) | 10 (0.6) | 7 (0.3) | 8 (0.1) | 31 (0.2) | 260.424 | 0.000 |
cystic PVLc | 1e | 13 (0.8) | 1e | 3e | 18 (0.1) | —d | 0.000 |
NECc | 8 (5.4) | 57 (3.5) | 45 (1.8) | 60 (0.6) | 170 (1.2) | 125.795 | 0.000 |
NEC stage IIIc | 1e | 5e | 1e | 1e | 8e | —d | 0.169 |
ROPc | 17 (11.5) | 69 (4.3) | 20 (0.8) | 38 (0.4) | 144 (1.1) | 356.511 | 0.000 |
ROP stage III+c | 3e | 9e | 2e | 7e | 21 (1.5) | —d | 0.790 |
Sepsisa | 20 (13.5) | 147 (9.1) | 114 (4.6) | 131 (1.4) | 412 (3.0) | 370.685 | 0.000 |
RDS respiratory distress syndrome, including grade I, II, III and IV, BPD bronchopulmonary dysplasia, including mild, moderate and severe BPD, ICH intracranial hemorrhage, IVH intraventricular hemorrhage, Severe IVH including grade III and IV, NEC necrotizing enterocolitis, including stage I, II and III, ROP retinopathy of prematurity, including grade 1, 2, 3, 4 and 5.
aProportion among all infants including survivors.
bMajor morbidity was defined as one or more of moderate/severe BPD, IVH stage ≥ III, cystic PVL, NEC stage III, ROP grade ≥ 3, and sepsis (early-onset sepsis, late-onset sepsis).
cProportion among infants who survived >7 days.
dFisher’s exact tests.
eNumerator less than 10.