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Results from enzymatic assays. Human GC1 activity as a function of free [Ca2+].
| GCAP1WT (n = 6) | GCAP1E111V b (n = 4) | GCAP1WT/E111V (n = 6) | 3XGCAP1WT/GCAP1E111V (n = 6) | |
|---|---|---|---|---|
| IC50 (nM) | 251 ± 19a | (10 ± 5)x103 | 694 ± 75 | 497 ± 49 |
| hc | 2.60 ± 0.42 | 0.83 ± 0.27 | 0.87 ± 0.18 | 1.49 ± 0.35 |
(a) reported data are mean ± s.e.m.
(b) data from. ref. 10.
