Fig. 5.
(A, top) The secondary structure calculated from the X-ray crystal structure of the NPM1 OD (PDB: 4N8M) using DSSP and the SSP scores for N130 calculated from solution state Cα and Cβ chemical shifts. (A, bottom) The SSP scores for NPM1 within the NPM1-p14ARF condensed phase calculated from solid state Cα and Cβ chemical shifts. The completeness of assignment is highlighted in light grey. (B) The X-ray crystal structure of the NPM1 OD, where residues that were assigned using CP-MAS ssNMR are highlighted in blue.