hsp90α1 and smyd1b expression was knocked down in Tg(ef1a:MuRF1a-GFP) and Tg(ef1a:MuRF2a-GFP) transgenic fish embryos. The MuRF1a-GFP and MuRF2a-GFP subcellular localization was determined by confocal microscopy in the hsp90α1 and smyd1b knockdown and control embryos.
A-C: MuRF1a-GFP localization in myofibers of zebrafish embryos injected with control-MO (A), Smyd1b-MO (B) or Hsp90α1-M0 (C) at 30 hpf.
D-F: A-C: MuRF2a-GFP localization in myofibers of zebrafish embryos injected with control-MO (D), Smyd1b-MO (E) or Hsp90α1-MQ (F) at 30 hpf.
Scale bar: 50 μm.