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. Author manuscript; available in PMC: 2019 Dec 28.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2018 May 28;1862(11):2518–2527. doi: 10.1016/j.bbagen.2018.05.018

Fig. 8.

Fig. 8.

INFɣ suppresses GPX4 expression in Healthy skin and Psoriatic Lesions. Significantly reduced GPX4 expression in clinical samples from INFɣ treated patients suggesting effective therapies such cytokine-based therapies may act in part by physiologic ferroptosis. Data from GEO data set GDS4607 comparing healthy patients (n = 10) to Psoriasis Patients with samples from nonlesional healthy skin (n = 10) and psoriatic skin (n = 10). Statistical Analysis: non-parametric Kruskall-Wallis test with bars indicating median raw values, ± interquartile range. **** and #### indicating p < 0.0001; *** or ### p < 0.001, * or # p < 0.05 and ns as p > 0.05.