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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Transl Stroke Res. 2019 Jun 28;11(2):254–266. doi: 10.1007/s12975-019-00712-z

Figure 5. Delayed inhibition of TRPM2 with tatM2NX improves memory function.

Figure 5.

A) Experimental timeline. B) Quantification of freezing behavior 24 hr after fear conditioning in a novel environment in MALE mice administered 20 mg/kg tatM2NX 6 days after recovery from CA/CPR and behavior testing initiated on day 7 after CA/CPR. C) Quantification of freezing behavior 24 hr after fear conditioning in a novel environment in FEMALE mice administered 20 mg/kg tatM2NX 6 days after recovery from CA/CPR and behavior testing initiated on day 7 after CA/CPR. D) Experimental timeline. E) Quantification of freezing behavior 24 hr after fear conditioning in a novel environment in male mice administered 20 mg/kg tatM2NX 29 days after recovery from CA/CPR and behavior testing initiated on day 30 after CA/CPR.