Table 1.

Equations for various kinetic models and their parameters

Model	Equation	Parameters definition
Zero order	C = kot	C: Concentration of drug ko: Zero order constant t: Time
First order	logCo - logCt = k1t/2.303	Co: Initial concentration Ct: Concentration at time t k1: First order constant t: Time
Higuchi Model	Q = k t1/2 H	Q: Amount of drug released in time t: Time kH: Higuchi constant t: Time
Hixson Crowell Model	Q 1/3 - Q 1/3 = k t o t HC	Qo: Initial amount of drug Qt: Remaining amount of rug at time t kHC: Hixson Crowell constant t: Time
Korsmeyer-Peppas Model	M - M = ktn t α	Mt - Mα: Fraction of drug released at time t k: Korsmeyer-Peppas constant t: Time n: Release exponent