Figure 2.

Concentration-response relaxant effect (mean ± SEM) of crocin on KCl (60 mM) induced contraction of tracheal smooth muscle in non-incubated (n = 8) and incubated tissues with (a) atropine (1 μM, n = 7), (b) glibenclamide (1 μM, n = 5). ^*p < 0.05, ^***p < 0.001, compared to saline (as indicated by zero in X axis of the figure). ⁺p < 0.05, ⁺⁺p < 0.01 ⁺⁺⁺p < 0.001, compared to non-incubated tissues. Statistical comparisons were performed using ANOVA with Tukey Kramer post-test