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Dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the ipsilateral of striatum and SN from different groups. Analysis of substantia nigra DA and DOPAC concentrations showed trehalose treatment protects cells from 6-OHDA-induced of striatal dopamine and dopamine metabolites depletion. A significant decrease in rats that were exposed to 6-OHDA as compared to control and treatment rats was seen, *P < 0.05, ** P < 0.01
