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PLA2R-AB most often occurs at or before the first documented prediagnostic hypoalbuminemia. A flow diagram of the temporal relationship between prediagnostic serum albumin and PLA2R-AB. As described in the Methods, the serial serum samples from the 59 PLA2R-AB–positive cases were also analyzed for serum albumin levels to determine whether albumin levels were normal or abnormally low before, at the same time, or after detectable PLA2R seropositivity.
