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PLA2R-AB is elevated months to years before prediagnostic hypoalbuminemia in some cases. Five cases showing evidence of seropositive PLA2R-AB before prediagnostic hypoalbuminemia. The horizontal dotted line is the cut-off for determining PLA2R-AB seropositivity. The first clinical evidence of prediagnostic hypoalbuminemia is indicated by time zero.
