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. 2019 Nov 1;31(1):67–83. doi: 10.1681/ASN.2019020125

Table 1.

Parameter values used to model albumin uptake along the human PT

Parameter Value Reference
Tubule length, L 17 mm 33
Tubule radius, R 18.5 µm 33
SNGFR 71 nl/min 30
Basal reabsorptive capacity, Vmax0 0.039 ng/s per mm2 a
Albumin concentration at half saturation, Km,A 31 µg/ml 35
Initial filtrate albumin concentration, A0 21.7 µg/ml 36,37
LMWP concentration at half saturation, Km,LMWP 10.4 µg/ml a
Initial filtrate LMWP concentration, LMWP0 67.3 µg/ml 36
Initial filtrate creatinine concentration 0.5 mg/dl 34
Fractional water reabsorption, fw 0.70 30
Fractional albumin reabsorption, fA 0.986 30
Fractional LMWP reabsorption, fLMWP 0.9997 39
a

Indicates fit parameter.