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. 2019 Dec 23;14:10047–10060. doi: 10.2147/IJN.S231167

Figure 1.

Figure 1

Triblock copolymer micelles loaded with VP exhibit tunable morphology, pH-sensitivity, and aqueous solubility. (A) Representative TEM images of both sVPM (left, scale bar= 100 nm) and fVPM (right, scale bar= 500 nm), (B) size and polydispersity index (PDI) of micelles (n=3, mean ± SD), (C) zeta potential of sVPM and fVPM in 10 mM NaCl, (D) turbidity measured with both free and encapsulated VP in fVPM at 2 mg/mL VP in 1× PBS (n=3, mean ± SD), (E) VP release from fVPM at 0, 1, 3, 5, and 10 hrs timepoints in buffers prepared at pH 5.0, 6.5, and 7.4 (n=3, mean ± SD, one-way ANOVA with Bonferroni’s multiple comparisons test (**p ≤ 0.01, ***p ≤ 0.001)).