Skip to main content
. 2019 Dec 23;14:10047–10060. doi: 10.2147/IJN.S231167

Figure 2.

Figure 2

NHA demonstrate significantly lower uptake efficiency and normalized geometric mean uptake of free VP, sVPM, and fVPM compared to patient-derived GBMs. (A) Consolidated uptake efficiency data from all three cell types and treatments at 7.8, 15.6, and 31.3 nM (n=4, mean ± SD, one-way ANOVA with Bonferroni’s multiple comparisons test (**p ≤ 0.01, ****p≤ 0.0001)). (B and C) Consolidated normalized geometric mean measurements at 62.5 nM (B) and 125 nM (C) VP treatment for all three tested cell types (n=4, mean ± SD, one-way ANOVA with Bonferroni’s multiple comparisons test (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001)). Cells were normalized to untreated controls of the same cell type.