Table 1.
Chemical/Physical Characteristics | sVPM | fVPM |
---|---|---|
PBAE base polymer/MW (Da) | B4S8m/5274 | B6S10m/6471 |
PEG-SH MW (Da) | 2000 | 800 |
Morphology | Spherical | Filamentous |
Hydrodynamic diameter (nm) | 156 ± 2 | 350 ± 20 |
PDI | 0.30 ± 0.02 | 0.46 ± 0.03 |
Zeta potential (mV) | 2 ± 6 | −3 ± 4 |
Loading capacity (%) | 5.62 | 6.82 |
Loading efficiency (%) | 33.7 | 14.6 |