Table 3.

Univariate and multivariate analysis of overall survival in 236 CRC patients

	Overall survival
	Univariate analysis		Multivariate analysis
	HR (95% CI)	p Value	HR (95% CI)	p Value
Age (yr)	0.895 (0.530–1.512)	0.679
Gender	1.222 (0.723–2.066)	0.455
Tumor location	1.168 (1.000–1.364)	0.050*	1.190 (0.994–1.423)	0.058
T classification	3.182 (1.705–5.937)	< 0.001*	2.938 (1.404–6.149)	0.004*
N classification	2.243 (1.615–3.115)	< 0.001*	0.912 (0.586–1.419)	0.002*
M classification	9.412 (5.481–16.162)	< 0.001*	9.385 (4.907–17.952)	< 0.001*
AJCC stage (III -IV vs I- II)	7.927 (3.394–18.511)	< 0.001*	3.369 (1.147–9.895)	0.027*
Recurrence	3.730 (2.144–6.488)	< 0.001*	5.667 (2.882–11.140)	< 0.001*
Differentiation	0.616 (0.370–1.025)	0.062
AGGF1	4.182 (2.384–7.333)	< 0.001*	3.320 (1.814–6.077)	< 0.001*

HR: hazard ratio; CI: confidence interval

* Significant differences