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. 2019 Dec 27;21:152. doi: 10.1186/s13058-019-1238-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Tumor-free survival of double mutant Pik3caH1047R;Trp53R270H;MMTV-Cre mice. a Pik3caH1047R;MMTV-Cre mice were crossed with Trp53R270Hflox mice to obtain the Pik3caH1047R;Trp53R270H;MMTV-Cre mice. b Kaplan–Meier plot depicting tumor-free survival of the indicated mouse lines. c Pie-chart representation of tumor types observed